RAJALAKSHMI CHOCKALINGAM

Understanding the role of Sars-cov viral peptide in fusion process of cell membrane

The thorough investigation of membrane fusion process is one of the main targets for the development of novel antiviral therapies to combat COVID-19. The mechanism adopted by viral peptide on host cell membranes has been studied using molecular simulation studies. This work primarily focus on the strategies adopted by peptide and its influence on the membrane bilayer properties. The structural and dynamic variations shown by the membranes are discussed at the molecular level. The role of membrane compositons on the response mechanism to peptides are addressed in detail.