Karan Saxena

Research Topic: Enhancing the sensitivity of Lateral Flow Immunoassays (LFIAs) for Point of Care (POC) Diagnostics.

Advisor: Bhushan Toley

Research Details

Lateral Flow Immunoassays (LFIAs) are rapid, paper-based, point-of-care medical diagnostic tests. A few common examples are the home pregnancy test strips and the CoViD-19 rapid antigen test (RAT) kits. LFAs provide rapid results, are low-cost, and are easy to use, making them a valuable tool for healthcare professionals and patients in resource-limited settings like rural areas where access to expensive medical diagnostic facilities may be limited. However, traditional LFAs have lower sensitivity and specificity compared to standard lab tests like ELISA and PCR. My research aims to enhance the sensitivity of LFAs by exploring various signal enhancement strategies. This could lead to more accurate and reliable results, ultimately improving patient care and health outcomes.

karansaxena at iisc.ac.in